| Date | Location | Result | |
| Nov 20, 2010 | Boiling Springs, NC | Gardner-Webb 10, VMI Keydets 7 | Box score |
| Nov 13, 2010 | Norfolk, Va. | Old Dominion 45, VMI Keydets 28 | Box score |
| Nov 06, 2010 | Lexington, Va. | COASTAL 31, VMI Keydets 3 | Box score |
| Oct 30, 2010 | West Point, N.Y. | Army 29, VMI Keydets 7 | Box score |
| Oct 23, 2010 | Charleston, S.C. | VMI Keydets 34, CSU 16 | Box score |
| Oct 16, 2010 | Lexington, Va. | LIBERTY 41, VMI Keydets 7 | Box score |
| Oct 9, 2010 | Stony Brook, N.Y. | Stony Brook 27, VMI Keydets 9 | Box score |
| Oct 2, 2010 | Lexington, Va. | VMI Keydets 24, Presbyterian College 13 | Box score |
| Sep 25, 2010 | Charlottesville, Va. | Virginia 48, VMI Keydets 7 | Box score |
| Sep 11, 2010 | Williamsburg, Va. | William and Mary 45, VMI Keydets 0 | Box score |
| Sep 4, 2010 | Lexington, Va. | VMI Keydets 48, Lock Haven 6 | Box score |